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Tamoxifen (Nolvadex)

Tamoxifen (Nolvadex) is a Selective Estrogen Receptor Modulator (SERM) used as PCT (Post-Cycle Therapy) after anabolic steroid cycles to restore natural testosterone production. It blocks estrogen receptors in breast tissue, preventing gynecomastia, and stimulates LH/FSH release to restart the HPTA (hypothalamic-pituitary-testicular axis).

  • Also known as: Nolvadex, Tamoxifen Citrate, Nolva
  • Form: oral
  • Half-life: 5–7 days
  • Typical cycle length: 4–6 weeks (PCT protocol)
  • Typical dose (men): 20–40 mg/day during PCT
  • Typical dose (women): Not applicable (medical use for breast cancer)
  • PCT required: no

Dosing by experience level

LevelDoseFrequencyNotes
Standard PCT40mg/day weeks 1-2, then 20mg/day weeks 3-4DailyStart 2 weeks after last long-ester injection
Gyno Prevention20 mg/day during cycleDailyOnly if experiencing gyno symptoms

Side effects

  • Hot flashes
  • Mood changes
  • Reduced libido temporarily
  • Vision changes (rare)
  • Blood clot risk (rare)

Common stacks

  • Clomid (Clomiphene)
  • hCG (human chorionic gonadotropin)
  • Anastrozole

Important notes

  • Standard PCT medication after steroid cycles
  • Often combined with Clomid for more complete HPTA recovery
  • Start PCT timing depends on ester used
  • Does not lower circulating estrogen — only blocks receptors in breast tissue
  • Use Anastrozole/Aromasin on-cycle to lower estrogen

Crestigen is an educational research reference. Nothing here is medical advice; many of these compounds are not approved for human use. Talk to a licensed clinician before using any substance.