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P21: 5 mg vial with 2 mL water
Quick answer
Adding 2 mL of bacteriostatic water to a 5 mg P21 vial gives 2.5 mg/mL (2500 mcg/mL), so each unit on a U-100 insulin syringe holds 25 mcg. A 50 mcg dose is 2 units (0.02 mL), and the vial holds about 100 doses of that size.
Concentration
- Vial: 5 mg P21
- Bacteriostatic water: 2 mL (the volume in the Crestigen protocol)
- Concentration: 2.5 mg/mL (2500 mcg/mL)
- 1 unit on a U-100 syringe = 25 mcg
P21 dose to syringe units
| Dose | Syringe units (U-100) | Volume | Doses per vial |
|---|---|---|---|
| 2 mcg (protocol dose) | 0.1 units, too small to measure reliably | 0.001 mL | 2500 |
| 5 mcg (protocol dose) | 0.2 units, too small to measure reliably | 0.002 mL | 1000 |
| 50 mcg | 2 units | 0.02 mL | 100 |
| 100 mcg | 4 units | 0.04 mL | 50 |
| 200 mcg | 8 units | 0.08 mL | 25 |
| 250 mcg | 10 units | 0.1 mL | 20 |
| 300 mcg | 12 units | 0.12 mL | 16 |
| 500 mcg | 20 units | 0.2 mL | 10 |
Units on a U-100 insulin syringe (100 units = 1 mL).
Common questions
How many units is 50 mcg of P21 from a 5 mg vial with 2 mL water?
50 mcg is 2 units (0.02 mL) on a U-100 insulin syringe. With 2 mL of water in a 5 mg vial, each unit holds 25 mcg. For comparison: 100 mcg = 4 units, 200 mcg = 8 units, 250 mcg = 10 units.
What is the concentration of a 5 mg P21 vial mixed with 2 mL of water?
5 mg divided by 2 mL is 2.5 mg/mL, or 2500 mcg per mL. On a U-100 syringe (100 units = 1 mL) that is 25 mcg per unit.
How many 50 mcg doses are in a 5 mg vial?
About 100. The water volume changes how many units each dose takes, not how many doses the vial holds.
How much water should I add to a 5 mg P21 vial?
2 mL is the volume used in the Crestigen P21 protocol. More water makes each dose a larger, easier-to-measure number of units; less water keeps injections smaller.
Other P21 vial and water combinations
- 5 mg vial + 1 mL water
- 5 mg vial + 2 mL water
- 5 mg vial + 3 mL water
Open this in the dosage calculator · Full P21 protocol, reconstitution and storage