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Tri-Heal (TB-500 + BPC-157 + KPV) dosage and protocol
Tri-Heal is a comprehensive healing blend combining TB-500 (25mg), BPC-157 (10mg), and KPV (10mg). This triple combination is studied for synergistic tissue repair, anti-inflammatory, and wound healing effects.
- Vial size: 45 mg
- Reconstitution: 3 mL bacteriostatic water
- Concentration: 15 mg/mL
- Administration: subcutaneous
Research areas
- Tissue Repair
- Wound Healing
- Anti-Inflammatory
- Recovery
Quick start
- Reconstitute: Add 3.0 mL bacteriostatic water to the 45 mg vial for 15 mg/mL total peptide
- Typical dose: 500-2000 mcg of total blend once daily, increased every two weeks
- Easy measuring: At 15 mg/mL, 1 unit (0.01 mL) on a U-100 syringe is 150 mcg; 500 mcg is about 3.3 units and 2000 mcg is about 13.3 units
- Storage: Frozen before reconstitution; refrigerate after and use within 30 days
Dosing protocol
| Phase | Dose | Frequency | Volume |
|---|---|---|---|
| Weeks 1–2 | 500 mcg | Once daily | 0.033 mL |
| Weeks 3–4 | 1000 mcg | Once daily | 0.067 mL |
| Weeks 5–6 | 1500 mcg | Once daily | 0.10 mL |
| Weeks 7–8 | 2000 mcg | Once daily | 0.133 mL |
How it works
Tri-Heal is a blend of three research peptides in a 25:10:10 mg ratio. TB-500 is based on thymosin beta-4, which binds G-actin and promotes cell migration, angiogenesis and reduced inflammation. BPC-157 is a 15-amino-acid peptide derived from a gastric protein; in rodent studies it promoted tendon, ligament, muscle and gut healing, with proposed mechanisms involving VEGF receptor signalling, nitric oxide pathways and growth factor expression. KPV is the C-terminal tripeptide (Lys-Pro-Val) of alpha-MSH and has anti-inflammatory effects, including reduced NF-κB activation, shown in cell models and rodent colitis models. The rationale for combining them is that each acts on a different part of repair: cell migration and vessel growth, growth factor signalling, and inflammation control. This is a theoretical synergy only. Evidence for each component comes mainly from animal and cell studies. Human data are very limited for BPC-157 and KPV, and injectable TB-500 has not been tested in published human trials. No studies have evaluated this specific combination, so its effects and safety as a blend are unknown.
Reconstitution steps
- Draw 3.0 mL bacteriostatic water with a sterile syringe
- Inject slowly down the vial wall; avoid foaming or direct stream onto the powder
- Gently swirl or roll until fully dissolved (do not shake)
- Label with date and concentration (15 mg/mL); refrigerate at 2–8°C, protected from light
Storage
Store frozen before reconstitution. Refrigerate after. Use within 30 days.
Important notes
- Research purposes only.
- Combines three healing mechanisms.
- Subcutaneous injection near injury site commonly studied.
Supplies
- Tri-Heal blend vial (45mg)
- 3 mL bacteriostatic water
- Insulin syringes (U-100, include 30- or 50-unit for early low-dose phases)
- Alcohol swabs
- Sharps container
Related peptides
Calculate your Tri-Heal (TB-500 + BPC-157 + KPV) dose in syringe units